Genomic sequencing is a method of determining the genetic makeup of an organism. Sequencing technologies have undergone several advancements in the past decade as researchers aim to improve the throughput and accuracy of base calling while also reducing costs.

Next-generation sequencing (NGS) is a massively parallel sequencing technology that is capable of sequencing millions of deoxyribonucleic acid (DNA) fragments simultaneously. The NGS workflow involves library/sample preparation followed by sequencing and data analysis. NGS has a wide range of applications, such as aiding in the diagnosis of various clinical conditions, automation of the NGS workflow, genetic screening, and selecting candidates for clinical trials. Moreover, NGS is also finding applications in areas beyond healthcare, such as in assessing the authenticity of food items, i.e., checking for cheaper substitutions of substances in food.

NGS informatics market was valued at $1,380.0 million in 2021 and is projected to reach $6,715.0 million by the end of 2032. The market is expected to grow at a CAGR of 15.21% during the forecast period 2022-2032. 

The market is driven by factors such as the low cost of sequencing platforms, increasing clinical applications of NGS in the field of oncology for the clinical management of cancer patients and mutation profiling, a tremendous rise in the amount of genomic data, the growing importance of population genomics studies and the establishment of various biobanks, advancements in big data technology, and government initiatives to support the advancement of NGS are expected to lead to higher demand for NGS informatics software.

Market Lifecycle Stage

The global NGS informatics market is in the development phase. The evolving regulatory landscape for clinical NGS and the growing number of gene mutations across various diseases are some of the major opportunities in the global NGS informatics market.

Market Segmentation Based on Products and Services 

The global NGS informatics market has been segmented into software solutions intended for storage and computing, tertiary data analysis, and automation and automating NGS workflows in laboratories, as well as NGS services such as sequencing services or consulting organizations in automating their NGS workflows

Market Segmentation Based on Application 

The advantages of NGS, such as its high sensitivity, quantitative nature, high dynamic range, and lack of hybridization, make it suitable for drug discovery. NGS has been used in the various steps of drug discovery, such as target identification and screening of compounds. NGS also plays a key role in the identification of rare variants responsible for various diseases. Detecting these variations in individual genomes helps identify the best course of treatment that will be effective for an individual and allows a greater number of targeted genes to be added to the testing panel. 

Regional Analysis 

Regions such as North America and Europe have a technologically advanced healthcare and genomics landscape, due to which these regions hold the maximum share in the global NGS informatics market. Regions such as Asia-Pacific, Latin America, and Rest-of-the-World are anticipated to register significant growth during the forecast period 2022-2032 owing to factors such as the rigorous research and development (R&D) related to NGS, advancements in big data technology, and increasing clinical applications of NGS in cancer.

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Some prominent established names in this market are:

•   Abbott Laboratories
  •    Agilent Technologies, Inc.
  •    Azenta, Inc.
  •    BGI Genomics Co., Ltd.
  •    DNAnexus, Inc.
  •    Eagle Genomics
  •    Euformatics
  •    F. Hoffmann-La Roche Ltd.
  •    Genalice BV
  •    Illumina, Inc.
  •    Partek Incorporated
  •    PerkinElmer, Inc.
  •    Precigen, Inc.
  •    QIAGEN N.V.
  •    SOPHiA GENETICS SA
  •    Thermo Fisher Scientific Inc.

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